Use of Transcranial Doppler as a Biomarker of CAR T Cell-Related Neurotoxicity

Discussion Our study demonstrates an association between increase in TCD MFV and the development of neurotoxicity, as well as timing of neurotoxicity onset. We believe that TCD ultrasound may be used as a bedside functional biomarker in CAR T-cell patients and may guide immunologic interventions to manage toxicity in this complex patient group.

http://cp.neurology.org/cgi/content/short/12/1/22?rss=1

Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Holroyd, K. B., Rubin, D. B., LaRose, S., Monk, A., Nikiforow, S., Jacobson, C., Vaitkevicius, H. Tags: Research Source Type: research