Drug Combinations for Mood Disorders and Physical Comorbidities That Need Attention: A Cross-Sectional National Database Survey
This study investigated combined prescriptions of drugs for
mood disorders and physical comorbidities that need special attention in the
light of frequent physical comorbidities in patients with mood disorders.
Methods We used the claims sampling data of 581,990 outpatients in January
2015 from the National Database of Health Insurance Claims and Specific Health
Checkups of Japan. Fisher’s exact test was performed to compare the
prescription rates of non-steroidal anti-inflammatory drugs (NSAIDs),
loop/thiazide diuretics, angiotensin-converting enzyme inhibitors,
and/or angiotensin II receptor blockers between lithium users and age-
and sex-matched non-lithium users; NSAIDs, antiplatelet drugs, and/or
anticoagulants between selective serotonin reuptake inhibitor
(SSRI)/serotonin-noradrenaline reuptake inhibitor (SNRI) users and
non-users; warfarin between mirtazapine users and non-users; and the proportions
of patients in the two groups with a diagnosis of somatic conditions for which
these medications were indicated and actually received them. A Bonferroni
corrected p-value of<0.05/3 was considered statistically
significant.
Results Prescriptions of the above-mentioned medications were less
frequent in lithium and mirtazapine users and comparable in SSRI/SNRI
users, compared to non-users (18.3...
Source: Pharmacopsychiatry - Category: Psychiatry Authors: Kuramochi, Shin Yatomi, Taisuke Uchida, Takahito Takeuchi, Hiroyoshi Mimura, Masaru Uchida, Hiroyuki Tags: Original Paper Source Type: research
More News: Coumadin | Databases & Libraries | Health Insurance | Insurance | Japan Health | Lithium | Men | Mirtazapine | Psychiatry | Statistics | Study | Warfarin