LRG1 expression reduced inflammation of sepsis-renal injury via activation of NLRP3 inflammasome by HIF-1 alpha

ConclusionsThe present study suggests that LRG1 expression reduced inflammation of sepsis-renal injury via activation of NLRP3 inflammasome by HIF-1 α, thereby may be a promising therapeutic target of sepsis-renal injury.

http://link.springer.com/10.1007/s13273-021-00214-w

Source: Molecular and Cellular Toxicology - January 26, 2022 Category: Cytology Source Type: research