ARDS, Pneumonia, and Sepsis Phenotyping Consortium Coordinating Center (U01 Clinical Trial Not Allowed)

Funding Opportunity RFA-HL-23-002 from the NIH Guide for Grants and Contracts. This funding opportunity annoucement (FOA) seeks applications for a Coordinating Center that will support the activities of a cooperative multi-siteAcute Respiratory Distress Syndrome (ARDS),Pneumonia, andSepsis Phenotyping Consortium (APS Consortium). The APS Consortium will seek to understand the heterogeneity and underlying mechanisms of critical illness syndromes and recovery, specifically in adults with ARDS, pneumonia, and/or sepsis, as well as the relationship and biological overlap among these syndromes. This will be accomplished through a prospective, longitudinal observational study with common data and biospecimen collection of 5,000 hospitalized adults with one or more of the following diagnoses: ARDS, pneumonia, or sepsis. It is expected that approximately half of the participants discharged from the hospital will have follow-up at 3, 6, and 12 months to facilitate understanding of long-term outcomes, including biological and physiological resolution of ARDS, pneumonia, and sepsis. Throughout the programs funding period, data (including imaging data) and biospecimens collected will be made available as a resource to the broader research community as rapidly and simply as possible.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding