Le LDL-cholest érol : une brique supplémentaire dans le mur de l'athérosclérose

Ann Cardiol Angeiol (Paris). 2022 Jan 14:S0003-3928(21)00167-0. doi: 10.1016/j.ancard.2021.10.020. Online ahead of print.ABSTRACTAtherosclerosis is one of the two major causes of mortality worldwide along with cancer and is responsible for myocardial infarction, stroke, and arteritis. Its pathophysiology is still partially understood which allows doubts referring to the preventive and curative treatments. Population screening for atherosclerosis remains marginal even though it should be the common practice. To encourage preventive screening and therapies, we propose a simple and easily understandable pathophysiology of atherosclerosis, explaining how the brick-wall of atheroma is build inside the intima of arteries using a metaphor: the LDL-cholesterol bricks, the oxidation cement, and the inflammatory mason.PMID:35039145 | DOI:10.1016/j.ancard.2021.10.020

Source: Atherosclerosis - January 18, 2022 Category: Cardiology Authors: Adrien Pasteur-Rousseau Alain Tedgui Source Type: research