Man vs. machine: comparison of pharmacogenetic expert counselling with a clinical medication support system in a study with 200 genotyped patients

ConclusionWith the computerized version of this approach, it became possible to score all combinations of all alternative drugs from each class of drugs administered ( “personalized medication landscape “) and to identify critical patients even before problems are reported (“medication alert”). Careful comparison of manual and score-based results shows that the incomplete manual consideration of genetic specialties and pharmacokinetic conflicts is responsi ble for most of the (minor) deviations between the two approaches. The meaning of the reduction of working time for experts by about 2 orders of magnitude should not be underestimated, as it enables practical application of personalized medicine in clinical routine.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research