Respiratory disturbances in fibromyalgia: A systematic review and meta-analysis of case control studies

Introduction: Fibromyalgia is a debilitating syndrome characterized by diffuse and chronic musculoskeletal pain and tender points in muscles and soft tissues. Studies have suggested that this dysfunction may cause deterioration of respiratory functions.Objective: We performed a systematic review and meta-analysis of case-control studies to explore the respiratory disturbances among persons with fibromyalgia in comparison with healthy adults.Methods: We systematically searched seven electronic databases: MEDLINE/PubMed, Web of Science, Scopus, Science Direct, Pedro database, CINAHL, and Cochrane Library for articles publishes before December 2020.Results: A total of seven studies were included in the systematic review. In the quantitative analysis, six studies were included. Pooled analysis showed that persons with fibromyalgia reported reduced Chest Expansion (mean difference -0.72, 95% confidence interval, -1.70 to 0.27, I2 =95%, p=0.016), Maximum Expiratory Pressure (mean difference -10.67, 95% confidence interval, -18.62 to -2.72, I2 =77%, p=0.009), Maximum Inspiratory Pressure (mean difference 11.04, 95% confidence interval, -14.45 to -7.62, I2 =0%, p<0.001) and Maximal Voluntary Ventilation (mean difference 11.79, 95% confidence interval, -16.80 to -7.78, I2 =0%, p<0.001).Measurements and Main Results: Persons with fibromyalgia experience respiratory disturbances. Respiratory disturbances were manifested such as reduced Chest Expansion, Maximum Expiratory Pressure,...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical problems Source Type: research