Cancers, Vol. 13, Pages 5906: Mutation Profile Variability in the Primary Tumor and Multiple Pulmonary Metastases of Clear Cell Renal Cell Carcinoma. A Review of the Literature and Analysis of Four Metastatic Cases

Conclusions: CCRCC shows heterogeneity between the primary tumor and its metastasis. Such mutational changes may be responsible for suboptimal treatment outcomes in targeted therapy settings.

Source: Cancers - November 24, 2021 Category: Cancer & Oncology Authors: Kristyna Prochazkova Nikola Ptakova Reza Alaghehbandan Sean R. Williamson Tom áš Vaněček Josef Vodicka Vladislav Treska Joanna Rogala Kristyna Pivovarcikova Kvetoslava Michalova Maryna Slisarenko Milan Hora Michal Michal Ondrej Hes Tags: Review Source Type: research