Growth hormone for in vitro fertilisation (IVF)

CONCLUSIONS: The use of adjuvant GH in IVF treatment protocols has uncertain effect on live birth rates and mean number of oocytes retrieved in normal responders. However, it slightly increases the number of oocytes retrieved and pregnancy rates in poor responders, while there is an uncertain effect on live birth rates in this group. The results however, need to be interpreted with caution, as the included trials were small and few in number, with significant bias and imprecision. Also, the dose and regimen of GH used in trials was variable. Therefore, further research is necessary to fully define the role of GH as adjuvant therapy in IVF.PMID:34808697 | DOI:10.1002/14651858.CD000099.pub4
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research