Salidroside orchestrates metabolic reprogramming by regulating the Hif-1 α signalling pathway in acute mountain sickness

CONCLUSIONS: These results suggest that Sal induces metabolic reprogramming by regulating the Hif-1α signalling pathway to activate compensatory responses, which may be the core mechanism underlying the effect of Rhodiola crenulata on the central nervous system.PMID:34739769 | DOI:10.1080/13880209.2021.1992449

Source: Pharmaceutical Biology - November 5, 2021 Category: Drugs & Pharmacology Authors: Xiaoning Yan Jie Liu Meixia Zhu Lirong Liu Yijun Chen Yinhuan Zhang Menghan Feng Zhixin Jia Hongbin Xiao Source Type: research