Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson ’s disease: removing axonal debris

ConclusionsThe present data suggest a physiological role of astrocytic phagocytosis of axonal debris for the medial forebrain bundle astrocytes, which may prevent the activation of microglia and the spread of retrograde axonal degeneration in PD.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research