Statin Intolerance and Non-Compliance: An Empiric Approach

Over the long-term, at least half of patients started on statins will discontinue them. Statin noncompliance can be defined as discontinuing therapy for whatever reason. This results from four causes: dysfunction of the health care system; fear of side effects (nocebo effect); disorders of the musculoskeletal system or other organs misconstrued as statin related; and true statin myotoxicity. Statin intolerance here represents discontinuation due to perceived side effects. For statin intolerance in patients with clinical atherosclerotic cardiovascular disease, the goal is an LDL level
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Advancing High Value Health Care Source Type: research