Driving out chronic lymphocytic leukemia with CAR T-cells

Chronic lymphocytic leukemia (CLL) is the most prevalent leukemia in the western hemisphere [1]. Better understanding of biologic, genetic and molecular aspects of CLL led to improved appreciation of its heterogeneity and, consequently, the development of more refined risk stratification models [2-12]. These models influenced clinical practice by better informing surveillance strategies, and adapting treatment intensity accordingly.

Source: Biology of Blood and Marrow Transplantation - October 13, 2021 Category: Hematology Authors: Mohamed A. Kharfan-Dabaja, Farah Yassine, Martha E. Gadd, Hong Qin Source Type: research