Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination

Discussion TF enhances zymosterol accumulation in oligodendrocytes and CNS myelin repair, a beneficial off-target effect that should be investigated in patients with multiple sclerosis.

http://nn.neurology.org/cgi/content/short/8/6/e1091?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - October 12, 2021 Category: Neurology Authors: Martin, E., Aigrot, M.-S., Lamari, F., Bachelin, C., Lubetzki, C., Oumesmar, B. N., Zalc, B., Stankoff, B. Tags: Multiple sclerosis Article Source Type: research