Equol Increases Cancer Progression via c-Myc Up-regulation [Molecular Bases of Disease]

This study therefore implicates c-Myc as a potential regulator of the cancer-promoting effects of equol via up-regulation of eIF4GI and selective initiation of translation on mRNAs that utilize non-canonical initiation, including certain oncogenes.

Source: Journal of Biological Chemistry - March 5, 2015 Category: Chemistry Authors: de la Parra, C., Borrero-Garcia, L. D., Cruz-Collazo, A., Schneider, R. J., Dharmawardhane, S. Tags: Protein Synthesis and Degradation Source Type: research