Endogenous microRNA triggered enzyme-free DNA logic self-assembly for amplified bioimaging and enhanced gene therapy via in situ generation of siRNAs

Small interfering RNA (siRNA) has emerged as a kind of promising therapeutic agents for cancer therapy. However, the off-target effect and degradation are the main challenges for siRNAs delivery. Herein, an en...

Source: Journal of Nanobiotechnology - September 26, 2021 Category: Nanotechnology Authors: Qinghua Jiang, Shuzhen Yue, Kaixin Yu, Tian Tian, Jian Zhang, Huijun Chu, Zhumei Cui and Sai Bi Tags: Research Source Type: research