Activation of Frizzled-7 attenuates blood –brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice

ConclusionsFrizzled-7 activation potentially attenuated BBB permeability and improved neurological deficits after ICH through Dvl /β-Catenin/WISP1 pathway. Frizzled-7 may be a potential target for the development of ICH therapeutic drugs.

http://link.springer.com/10.1186/s12987-021-00278-9

Source: Fluids and Barriers of the CNS - September 26, 2021 Category: Neuroscience Source Type: research