Bing-Neel syndrome: update on the diagnosis and treatment
Waldenstrom macroglobulinemia (WM) is a rare lymphoid neoplasm characterized by unregulated growth of immunoglobulin M (IgM)-producing monoclonal lymphoplasmacytic lymphocytes (LPLs) in the bone marrow. It constitutes only 1-2% of hematologic malignancies and usually affects males between 50 and 70 years1. The manifestations of WM are usually related to IgM paraproteinemia and include hyperviscosity, hemolytic anemia, and/or peripheral neuropathy. The lymphoplasmacytic proliferation can involve extramedullary tissue in 20% of cases of WM2.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Abdelrahman Nanah, Samer Al Hadidi Tags: Review article Source Type: research
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