Usefulness of supplementary ultrasound surveillance in the detection of a second breast cancer in patients with ductal carcinoma in situ

CONCLUSION: In DCIS patients, the rate of second breast cancers was 7.5%. Breast conservation, involved margins after lumpectomy and shortened hormonal therapy were associated with second cancers. Patients with involved margins after lumpectomy have the highest cancer detection rate and minimal unnecessary biopsies and follow-ups. Hence, ipsilateral breast ultrasound surveillance could be personalized for this high-risk group with mammographically dense breasts.PMID:34544658 | DOI:10.1016/j.clbc.2021.08.006
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research

Related Links:

CONCLUSION: Our findings revealed a critical role of the IPW-miR-29c-ID2 axis in DCIS formation and suggested potential clinical use of toyocamycin for the treatment of DCIS.PMID:35078502 | DOI:10.1186/s13058-022-01504-4
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research
AbstractPurposeDespite recommendations from national organizations supporting the use of lymph node assessment (LNA) among patients with ductal carcinoma in situ (DCIS) at time of mastectomy, variation in practice patterns across the United States has been observed. However, few studies have evaluated LNA differences and rurality.MethodsData from the SEER Patterns of Care studies were used to identify women who underwent mastectomy for newly diagnosed DCIS during 2000, 2005, 2010, and 2015. Weighted multivariate logistic regression was used to evaluate the association between rural –urban residence and the use of LNA...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: Antidepressant use after DCIS diagnosis was associated with an increased risk of subsequent breast cancer in women. Further studies are needed to confirm the associations observed.PMID:35061141 | DOI:10.1007/s10552-021-01551-w
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research
Conclusion The rates of BRCA1, BRCA2 and TP53 PVs are high in very early onset breast cancer, with limited benefit from testing of additional breast cancer-associated genes.
Source: Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Open access Cancer genetics Source Type: research
CONCLUSIONS: CWPF is an option for treatment of centrally located breast cancers/DCIS needing nipple-areola complex excision for patients wishing to avoid mastectomy. Patients with small to medium-sized non-ptotic breasts are suitable, and need to be carefully selected.PMID:35047062 | PMC:PMC8723741 | DOI:10.3332/ecancer.2021.1311
Source: Ecancermedicalscience - Category: Cancer & Oncology Authors: Source Type: research
ConclusionThe ADC-based CNN model can improve the differentiation of IBC from DCIS with higher accuracy and less time.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
In conclusion, DCIS/invasion ratio >  0.375 in CNB was identified as a predictor of Ext-DCIS >  2.5 in resection specimens, suggesting that an approach combining DCIS/invasion ratio from CNB with preoperative staging may better predict the extent of DCIS and facilitate better surgical planning.
Source: Virchows Archiv - Category: Pathology Source Type: research
Source: European Radiology - Category: Radiology Source Type: research
Purpose of review Ductal carcinoma in situ (DCIS) is a noninvasive stage of disease but understood to be a nonobligate precursor to invasive breast cancer. As such, women with DCIS are routinely recommended for standard breast cancer treatment to prevent progression to invasive disease. DCIS, however, represents a heterogeneous group of lesions that differs in its biologic behavior and risk of progression. Thus, optimal treatment is unclear. This review presents the clinical trials evaluating the de-escalation of therapy, attempts at risk stratification, and future directions in the management of this disease. Recen...
Source: Current Opinion in Obstetrics and Gynecology - Category: OBGYN Tags: BREAST CANCER: Edited by Gottfried E. Konecny Source Type: research
J Breast Cancer. 2021 Dec;24(6):520-530. doi: 10.4048/jbc.2021.24.e52.ABSTRACTPURPOSE: The oncoplastic breast-conserving surgery (OPS) technique, combined with the principles of oncological safety and plastic surgery, results in complete tumor resection while preserving the natural appearance of the breast. The purpose of this study was to evaluate the long-term oncological results after OPS compared with conventional breast-conserving surgery (BCS) for early breast cancer.METHODS: The medical records of patients who underwent breast cancer surgery and adjuvant radiation therapy at Seoul National University Hospital betwee...
Source: Journal of Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
More News: Breast Cancer | Breast Carcinoma | Breast Conservation Surgery | Breast Lumpectomy | Cancer | Cancer & Oncology | Carcinoma | Carcinoma in Situ | DCIS (Ductal Carcinoma in Situ) | Ductal Carcinoma | Hormonal Therapy | Hormones | Lumpectomy | Mammography | Study | Ultrasound