Biodosimetry in interventional radiology: cutaneous-based immunoassay for anticipating risks of dermatitis

ConclusionsWith this study, we showed that DosiKit provides a useful way for mapping the actually absorbed doses, allowing to identify patients overexposed in interventional radiology procedures, and thus for anticipating risk of developing dermatitis.Key Points• DosiKit is a new external irradiation biodosimetry device, based on the dose-dependent relationship between irradiation dose and radiation-induced H2AX protein phosphorylation in hair follicles.• DosiKit was tested over 95 patients treated with neuroradiological interventions.• The threshold sensitivity of the DosiKit immunoassay was estimated around 700 mGy and DosiKit provides a useful way for mapping the actually absorbed doses.
Source: European Radiology - Category: Radiology Source Type: research