Estrogen augmented visceral pain and colonic neuron modulation in a double-hit model of prenatal and adult stress

CONCLUSION: This study adds to the evidence that estrogen-dependent sensitization of primary afferent colon neurons is involved in the development of chronic stress-induced visceral hypersensitivity in female rats.PMID:34497435 | PMC:PMC8384739 | DOI:10.3748/wjg.v27.i30.5060

Source: World Journal of Gastroenterology : WJG - September 9, 2021 Category: Gastroenterology Authors: Jing-Hong Chen Ying Sun Pei-Jun Ju Jin-Bao Wei Qing-Jie Li John H Winston Source Type: research