Serum PIVKA-II and alpha-fetoprotein at virological remission predicts hepatocellular carcinoma in chronic hepatitis B related cirrhosis

CONCLUSIONS: In patients with CHB-related cirrhosis, serum alpha-fetoprotein >7 ng/mL and PIVKA-II >50 mAU/mL at the time of antiviral therapy-induced VR is associated with a greater risk of HCC. PIVKA-II is a predictive marker for HCC in patients with low normal alpha-fetoprotein level.PMID:34452785 | DOI:10.1016/j.jfma.2021.08.003

Source: J Formos Med Assoc - August 28, 2021 Category: General Medicine Authors: Tung-Hung Su Cheng-Yuan Peng Shan-Han Chang Tai-Chung Tseng Chun-Jen Liu Chi-Ling Chen Chen-Hua Liu Hung-Chih Yang Pei-Jer Chen Jia-Horng Kao Source Type: research