Epidemiology of Parkinson ’s Disease in Chile

Conclusion: The prevalence and incidence observed in the Chilean population are consistent with studies from other countries.Neuroepidemiology
Source: Neuroepidemiology - Category: Epidemiology Source Type: research

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What started with an unsolicited offer last October turned into major acquisition of Adamas Pharmaceuticals by an East Coast specialty drug maker one year later.
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
What started with an unsolicited offer last October turned into major acquisition of Adamas Pharmaceuticals by an East Coast specialty drug maker one year later.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
This article presents the results of combined osteological and archival research into the demographics, preservation condition, taphonomy, pathology, cultural modification, and collecting history of that specific portion of the Parkinson collection of human crania from New Britain, collected c. 1897, currently housed in the Etnografiska Museet (Ethnography Museum), Stockholm, Sweden. This assemblage of crania (n = 45) was acquired by Richard Heinrich Robert Parkinson (1844–1909), a Danish explorer and anthropologist initially in the employ of the Hamburg based J. C Goddefroy&Sohn in Samoa trading fi...
Source: International Journal of Osteoarchaeology - Category: Science Authors: Tags: RESEARCH ARTICLE Source Type: research
Background: Various cerebrospinal fluid (CSF) biomarkers are studied in Parkinson ’s disease (PD) and atypical parkinsonian syndromes (APS). Several studies found reduced 5-hydroxyindoleacetic acid (5-HIAA), the main serotonin metabolite, in PD. There is little evidence regarding its levels in APS. Methods: We measured 5-HIAA in the CSF of 90 PD patients, 16 MSA patients, 26 pr ogressive supranuclear palsy (PSP) patients, 11 corticobasal degeneration (CBD) patients, and 31 controls. We also compared the values in depressed and non-depressed patients. Results: There was a statistically significant difference in CSF 5...
Source: Neurodegenerative Diseases - Category: Neurology Source Type: research
Source: Nutritional Neuroscience - Category: Nutrition Authors: Source Type: research
This case-control study examines whether prior influenza and other infections are associated with Parkinson disease more than 10 years after infection using data from 1977 to 2016 from the Danish National Patient Registry.
Source: JAMA Neurology - Category: Neurology Source Type: research
The phrase “change is the only constant” has never been more apt than in the current environment where we constantly hear stories about cuts, increased overheads and competitive pressures. How we deal with change will determine our future success. Last week I was sent an email by a friend who was informing me, that for various reasons, he was leaving his employment and looking for a new challenge. In the message he sent he shared a powerful metaphor that sums up the attitudes that can be extremely helpful when dealing with change – in whatever shape it comes. It’s not important whether we ...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Life change Source Type: news
This study confirmed that the PSI could be a quantitative index of vascular aging and has potential for use in inferring arterial stiffness with an advantage over the rAIx. A Profile of Michael Greve and the Segment of the Longevity Industry that He Supports https://www.fightaging.org/archives/2021/10/a-profile-of-michael-greve-and-the-segment-of-the-longevity-industry-that-he-supports/ Would that the popular media produced more popular science articles about the longevity industry like this one. It is not just a profile of someone trying to make a difference in the world by advancing the state of medici...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, we tried to clarify the link between CI and UPDRS part II (off-on), which was calculated by subtracting part II (on) from part II (off), in patients with Parkinson's disease (PD).
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research
This study aims to explore the neuroprotection of B-type CPO (CPO-B) against 1-methyl-4-phenylpyridinium (MPP+)-mediated cytotoxicity and the molecular mechanisms underlying its protection. The results demonstrated that CPO-B showed protection by increasing cell viability, attenuating an intracellular level of reactive oxygen species, downregulating cleaved caspase-3 expression, and upregulating the Bcl-2/Bax ratio. Moreover, CPO-B completely blocked the dephosphorylation of extracellular, signal-regulated kinase 1 and 2 (Erk1/2) caused by MPP+. Treatment with an Erk1/2 inhibitor, SCH772984, significantly abolished the neu...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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