P –078 Prognostic factors for male fertility recovery after microsurgical varicocelectomy

AbstractStudy questionWhat clinical and laboratory parameters are reliable predictors of spontaneous pregnancy (SP) after microsurgical varicocelectomy in men from infertile couples?Summary answerPredictors of SP after microsurgical varicocele repair are the male age, baseline total sperm motility, and postoperative increase level of TPMSC.What is known alreadyVaricocele is the most common correctable cause of male subfertility. According to the recent meta-analyses and studies, microsurgical varicocelectomy is the “golden standard” method for varicocele repair. However, it is still unclear why at least one-third of subfertile men do not experience improvement in semen parameters and more than half of them do not report fertility recovery after varicocelectomy. There is no consensus so far on the factors a ffecting the efficacy of varicocele repair in men from infertile couples.Study design, size, durationThis retrospective study comprises 93 men from infertile couples, with palpable varicocele, astheno-/oligozoospermia, and who underwent microsurgical subinguinal or inguinal varicocelectomy from September 2015 to May 2019.Participants/materials, setting, methodsThe changes in semen analysis were assessed (in 3 –6 months after surgery) according to WHO–2010, spontaneous pregnancy (SP) rates after surgery also were considered. A stepwise discriminant analysis was performed to identify predictors of SP after varicocelectomy. An increase in TPMSC by at least 12.5 million...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research