Genetically determined hypertensive phenotype affects gut microbiota composition, but not vice versa

Conclusion: Genetically induced hypertension in SHR is associated with alterations in the composition of gut bacteria and histological morphology of the colon. An inter-strain fecal transplant does not affect BP and does not produce long-term changes in gut bacteria composition. We propose that the impact of the host genotype and/or phenotype on the gut bacteria may be greater than the impact of the gut bacteria on the host BP.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Animal studies Source Type: research