SPP1 Regulates Radiotherapy Sensitivity of Gastric Adenocarcinoma via the Wnt/Beta-Catenin Pathway

CONCLUSION: This study demonstrates that SPP1 suppresses Wnt/β-catenin signaling to enhance the radiosensitivity of GAC via inhibiting invasion and accelerating DNA damage, G2/M phase arrest, and apoptosis.PMID:34367279 | PMC:PMC8337119 | DOI:10.1155/2021/1642852

Source: Journal of Oncology - August 9, 2021 Category: Cancer & Oncology Authors: Gangyi Sun Ziyi Shang Wenjia Liu Source Type: research