Airwave oscillometry to measure lung function in children with Down syndrome

CONCLUSIONS: Measures of pulmonary function were successfully obtained using airwave oscillometry in children with Down syndrome, which supports its use in this high-risk population.IMPACT: Children with Down syndrome are at risk for significant pulmonary co-morbidities, but the gold standard metric of lung function, spirometry, may not be feasible in children with intellectual disabilities. This may limit the population's enrollment in clinical trials and in standardized clinical care. In this prospective study of lung function in children with Down syndrome, airwave oscillometry was successful in 76% of participants but spirometry was successful in only 12%. This study reinforces that measures of pulmonary function can be obtained successfully using airwave oscillometry in children with Down syndrome, which supports its use in this high-risk population.PMID:34326475 | DOI:10.1038/s41390-021-01664-7

Source: Pediatric Research - July 30, 2021 Category: Pediatrics Authors: Monica L Vielkind Katharine L Hamlington Kristine Wolter-Warmerdam Maxene R Meier Andrew H Liu Francis J Hickey Mark A Brown Emily M DeBoer Source Type: research