Bacteriophages as tools for biofilm biocontrol in different fields
Biofouling. 2021 Jul 26:1-21. doi: 10.1080/08927014.2021.1955866. Online ahead of print.ABSTRACTMicrobial biofilms are difficult to control due to the limited accessibility that antimicrobial drugs and chemicals have to the entrapped inner cells. The extracellular matrix, binds water, contributes to altered cell physiology within biofilms and act as a barrier for most antiproliferative molecules. Thus, new strategies need to be developed to overcome biofilm vitality. In this review, based on 223 documents, the advantages, recommendations, and limitations of using bacteriophages as 'biofilm predators' are presented. The plausibility of using phages (bacteriophages and mycoviruses) to control biofilms grown in different environments is also discussed. The topics covered here include recent historical experiences in biofilm control/eradication using phages in medicine, dentistry, veterinary, and food industries, the pros and cons of their use, and the development of microbial resistance/immunity to such viruses.PMID:34304662 | DOI:10.1080/08927014.2021.1955866
Source: Biofouling - Category: Molecular Biology Authors: Camila Mendes Figueiredo Marilia Silva Malvezzi Karwowski Romeu Cassiano Pucci da Silva Ramos Nicoly Subtil de Oliveira Lorena Caroline Pe ña Everdan Carneiro Renata Ernlund Freitas de Macedo Edvaldo Antonio Ribeiro Rosa Source Type: research
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