Radiomics and radiogenomics in head and neck squamous cell carcinoma: potential contribution to patient management and challenges

Heterogeneity is a hallmark of head and neck squamous cell carcinoma (HNSCC) and this is manifested at different levels, most notably in its complex anatomy including several potential primary tumor sites, various carcinogenic pathways, a broad genomic landscape, and high tumor microenvironment variability. This molecular and biological heterogeneity is reflected in the different clinical outcomes in patients treated with the same standard therapy, in both locally advanced and recurrent/metastatic settings.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Source Type: research