Role of Hic-5 in the formation of microvilli-like structures and the monocyte-endothelial interaction that accelerates atherosclerosis

Conclusion
Hic-5 in ECs plays an important role in the formation of microvilli-like structures and in the interaction between ECs and monocytes, leading to monocyte recruitment and subsequent development of atherosclerosis.

Source: Cardiovascular Research - February 23, 2015 Category: Cardiology Authors: Arita-Okubo, S., Kim-Kaneyama, J.-r., Lei, X.-F., Fu, W.-G., Ohnishi, K., Takeya, M., Miyauchi, A., Honda, H., Itabe, H., Miyazaki, T., Miyazaki, A. Tags: Vascular biology Source Type: research