Involvement of the Auditory Pathway in Spinocerebellar Ataxia Type 7

Conclusions: BAEP tests revealed functional involvement of the auditory pathway in SCA7 (mainly at) peripheral portions, which gave new insights into the disease physiopathology different from SCA2 and may unravel distinct pathoanatomical effects of polyQ expansions in the central nervous system.Significance: These findings offer important insights into the distinctive disease mechanisms in SCA7 and SCA2, which could be useful for differential diagnosis and designing specific precision medicine approaches for both conditions.Neurodegener Dis

Source: Neurodegenerative Diseases - July 9, 2021 Category: Neurology Source Type: research