Daptomycin Pharmacokinetics and Pharmacodynamics in Patients on Methadone Substitution Therapy

ConclusionsTreatment ofStaphylococcus aureus IE in IDUs on methadone treatment requires the use of high daptomycin daily doses in order to achieve satisfactory pharmacodynamic parameters. Close monitoring of the daptomycin plasma concentration is suggested.
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research