In-silico evaluation of Malawi essential medicines and reactive metabolites for potential drug-induced toxicities

CONCLUSIONS: A large number of drugs had the potential to cause various systemic toxicities. But the results need to be interpreted cautiously since the clinical translation of QSAR-based predictions depends on many factors. In addition, inconsistencies have been reported between screening results amongst different models.PMID:34134770 | DOI:10.1186/s40360-021-00499-6
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Authors: Source Type: research