Breast cancer risk clouds fertility care

Breast cancer is a leading cause of death among reproductive-age women and, understandably, a source of anxiety and fear for many. Several risk factors for this often-devastating disease have been identified, including family history, obesity, socioeconomic status, and diet. Nulliparity, both elective and because of infertility, additionally confers an increased risk. Countless publications have addressed the association between exogenous hormones and breast cancer, but the link between fertility medications and cancer is unclear.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research

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This article focuses on various epigenetic factors involved in the pathogenesis of rheumatoid arthritis. Further, various epigenetic therapies that might be successful in inhibiting these epigenetic modifications are summarized. Several therapeutic agents alter the epigenetic modifications occurring in various diseases and many of the epigenetic therapies are under pre-clinical and clinical trial. However, exploring these epigenetic prognostic biomarkers would give a broader perspective and provide more ideas and knowledge regarding the process and pathways through which the diseases occur, and also combining various thera...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Biomedical Engineering Scientific Interest Group(BMESIG) seminar series: Lecture by Dr.Natalie Artzi, Assistant Professor of Medicine, Brigham and Women ’ s Hospital, Harvard Medical School; Principal Research Scientist, MIT; Associate Member, Broad Institute of Harvard and MIT. The power of leveraging the patient ’ s own immune system to fight diseases is increasingly being recognized. This talk will explore medical technologies being developed that harness lessons from biomaterial development for drug delivery systems to those that will reprogram the immune system to generate robust and long-lasting curative ...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
ConclusionThis study found that teach-back interventions have positive health outcomes including happiness, uncertainty, self-efficacy, self-management behavior, symptom experience, distress, anxiety, and health literacy among cancer patients. However, it found no effects with regard to drug administration, functional measurements, or satisfaction. Future research should continuously examine the teach-back approach and assess its positive health outcomes for cancer patients.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionConducting RCTs using a state cannabis program is feasible. The addition of MC to standard oncology care was well-tolerated and may lead to improved pain control and lower opioid requirements. Conducting larger RCTs with MC in state-sponsored programs may guide oncology providers on how to safely and effectively incorporate MC for interested patients.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
AbstractThe management of febrile neutropenia (FN) in pediatrics is evolving. Our objective was to describe current practices for the care of patients with FN in pediatric oncology centers in Latin America and identify areas for practice improvement. We used an online survey to enroll eligible healthcare providers who treat children with cancer in Latin America. The survey addressed respondents ’ characteristics, the environment of care, and FN care practices, including risk assessment, criteria for hospitalization, initial management of FN, evaluation, antibiotic administration, and discharge. From 220 surveys sent,...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionThis study contributes to existing literature in that it found patients who received inpatient rehabilitation services demonstrate significant improvement in their functional status despite reporting CRF upon admission to a long-term acute care hospital oncology unit.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionsResults suggest that psychological distress and lower HRQoL should be taken into account while promoting a healthy diet in overweight or obese CRC survivors since these factors may hinder adherence to a healthy diet.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionThe benefits of using antimicrobial prophylaxis were less supported. Enhancing diagnostic laboratory and medical complication surveillance and periodic evaluation of institutional data during post-chemotherapy neutropenia and NF in relation to antimicrobial prophylaxis is promising in providing insights to redefine the risk –benefit accounts of using prophylaxis.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
Conclusion The periconceptional environment and lifestyle factors modify sperm epigenome. This alteration might be maintained in the zygote and throughout development, thereby leading to the inheritance of newly acquired pathologies. The role of sperm miRNA, not only as innovative markers of fertility issues but also as vectors involved in the inheritance of paternal diseases, appears to be crucial. Overweight and obesity seem to alter sperm miRNA profile, thereby leading to transmission of different miRNA profiles in zygote, with consequences on embryo development. In long term, metabolic disorders have been described in...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
By Katrina Mark, MD 1. Fertility naturally declines as we age That alone doesn’t mean you should start to worry. The general advice I give a woman is if she has been trying to become pregnant for a full year with no luck, she might consider a fertility evaluation. For a woman over age 35, she might consider it after six months. If a woman is younger and has irregular periods, it’s likely she isn’t regularly ovulating, so she might want to be evaluated sooner. 2. Sometimes there’s a reason for infertility – and sometimes, there’s not There are some things we know cause infertility. About...
Source: Life in a Medical Center - Category: Universities & Medical Training Authors: Tags: Health Tips Women's Health fertility Katrina Mark obgyn UMMC Source Type: blogs
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