Rg1 exerts protective effect in CPZ-induced demyelination mouse model via inhibiting CXCL10-mediated glial response

In conclusion, CXCL10 mediates the protective role of Rg1 in CPZ-induced demyelination mouse model. This study provides new insight into potential disease-modifying therapies for myelin abnormalities.PMID:34103690 | DOI:10.1038/s41401-021-00696-3

Source: Acta Pharmacologica Sinica - June 9, 2021 Category: Drugs & Pharmacology Authors: Yi-Xiao Dong Shi-Feng Chu Sha-Sha Wang Ya-Juan Tian Wen-Bin He Yu-Sheng Du Zhen-Zhen Wang Xu Yan Zhao Zhang Nai-Hong Chen Source Type: research