The influence of single nucleotide polymorphisms of NOD2 or CD14 on the risk of Mycobacterium tuberculosis diseases: a systematic review

ConclusionsTheCD14 rs2569190 and rs2569191 polymorphisms may influence riskof Mtb diseases depending on the allele. Furthermore, there is significant association betweenNOD2 SNPs rs1861759 and rs7194886 and augmented riskof Mtb diseases, especially in persons of Chinese ethnicity. The referred polymorphisms ofCD14 andNOD2 genes likely play an important role in riskof Mtb diseases and pathology and may be affected by ethnicity.Systematic review registrationCRD42020186523
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research