A reverse stroke characterizes the force generation of cardiac myofilaments, leading to an understanding of heart function [Biophysics and Computational Biology]

Changes in the molecular properties of cardiac myosin strongly affect the interactions of myosin with actin that result in cardiac contraction and relaxation. However, it remains unclear how myosin molecules work together in cardiac myofilaments and which properties of the individual myosin molecules impact force production to drive cardiac contractility....
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biophysics and Computational Biology Biological Sciences Source Type: research