Infused autograft-absolute lymphocyte count predicts superior survival in Diffuse Large B-Cell Lymphoma patients post-autologous peripheral blood hematopoietic stem cell transplantation: a matched-control study
Day 15 absolute lymphocyte count (ALC-15) recovery after autologous peripheral blood hematopoietic stem cell transplantation (APBHSCT) is recognized as a prognostic factor for survival [1-3]. ALC-15 recovery is directly dependent on the amount of collected and infused autograft-absolute lymphocyte count (A-ALC) [4-5]. Retrospective studies have reported that the A-ALC is also a prognostic factor for clinical outcomes post-APBHSCT [4-6]. Our group published a double-blind phase III study showing that patients infused with an A-ALC ≥ 0.5 × 109 cells/kg compared with patients infused with an A-ALC
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Luis F. Porrata, Edwin A. Burglaster, Jeffrey L. Winters, Eapen Jacob, David J. Inwards, Stephen M. Ansell, Ivana N. Micallef, Patrick B. Johnston, Jose Villasboas, Jonas Paludo, Svetomir N. Markovic Source Type: research
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