Infused autograft-absolute lymphocyte count predicts superior survival in Diffuse Large B-Cell Lymphoma patients post-autologous peripheral blood hematopoietic stem cell transplantation: a matched-control study

Day 15 absolute lymphocyte count (ALC-15) recovery after autologous peripheral blood hematopoietic stem cell transplantation (APBHSCT) is recognized as a prognostic factor for survival [1-3]. ALC-15 recovery is directly dependent on the amount of collected and infused autograft-absolute lymphocyte count (A-ALC) [4-5]. Retrospective studies have reported that the A-ALC is also a prognostic factor for clinical outcomes post-APBHSCT [4-6]. Our group published a double-blind phase III study showing that patients infused with an A-ALC ≥ 0.5 × 109 cells/kg compared with patients infused with an A-ALC
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research