How to handle the delayed or missed dose of rivaroxaban in patients with non-valvular atrial fibrillation: model-informed remedial dosing

CONCLUSION: EHRA guide may not provide optimal remedial strategies. PK/PD modelling and simulation provide valid evidence on the remedial dosing regimen of rivaroxaban, which could help to minimise the risk of bleeding and thromboembolism.PMID:34058934 | DOI:10.1080/17512433.2021.1937126

Source: Pharmacological Reviews - June 1, 2021 Category: Drugs & Pharmacology Authors: Xiao-Qin Liu Yi-Wei Yin Chen-Yu Wang Zi-Ran Li Xiao Zhu Zheng Jiao Source Type: research