Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients

ConclusionThis study provides converging murine and human data demonstrating the selective structural disruption of hypothalamic inputs in ALS as a promising factor contributing to the origin of the hypermetabolic phenotype.

Source: Translational Neurodegeneration - May 31, 2021 Category: Neurology Source Type: research