Kappa-Free Light Chains in CSF Predict Early Multiple Sclerosis Disease Activity

Conclusion
High -FLC index predicts early MS disease activity.

Classification of Evidence
This study provides Class II evidence that in patients with early MS, high -FLC index is an independent risk factor for early second clinical attack.

Source: Neurology Neuroimmunology and Neuroinflammation - May 28, 2021 Category: Neurology Authors: Berek, K., Bsteh, G., Auer, M., Di Pauli, F., Grams, A., Milosavljevic, D., Poskaite, P., Schnabl, C., Wurth, S., Zinganell, A., Berger, T., Walde, J., Deisenhammer, F., Hegen, H. Tags: Cerebrospinal Fluid, Class II, Multiple sclerosis Article Source Type: research