Serologic Response to Messenger RNA Coronavirus Disease 2019 Vaccines in Inflammatory Bowel Disease Patients Receiving Biologic Therapies

Inflammatory bowel disease (IBD) patients with Crohn ’s disease and ulcerative colitis have been considered at increased risk of severe coronavirus disease 2019 (COVID-19) because they are often treated with immunosuppressive medications. Indeed, steroids and thiopurines in combination therapy with tumor necrosis factor (TNF) antagonists, but not TN F antagonist monotherapy, have been associated with a risk of severe COVID-19 in IBD patients.1,2 Expert consensus advocates that IBD patients should be vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Brief Communication Source Type: research