Unforeseen links to chronic pancreatitis found in cancer-related signals

(Osaka University) Researchers from Osaka University have demonstrated that two signaling pathways, the PI3K and the Hippo pathways earlier implicated in the development of pancreatic cancer, are responsible for the development and progression of chronic pancreatitis. Experiments in animal models, corroboration by laboratory evidence, and studies of human diseased tissue suggest that targeting pathologically upregulated Connective Tissue Growth Factor (CTGF) may be a useful therapeutic strategy against this disease.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news