Worenine reverses the Warburg effect and inhibits colon cancer cell growth by negatively regulating HIF-1alpha

CONCLUSION: It is suggested that worenine targets HIF-1α to inhibit colorectal cancer cell growth, proliferation, cell cycle progression and the Warburg effect.PMID:34006215 | DOI:10.1186/s11658-021-00263-y

Source: Mol Biol Cell - May 19, 2021 Category: Molecular Biology Authors: Lijiang Ji Weixing Shen Feng Zhang Jie Qian Jie Jiang Liping Weng Jiani Tan Liu Li Yugen Chen Haibo Cheng Dongdong Sun Source Type: research