Killing of by azithromycin, clarithromycin, erythromycin, telithromycin and gemifloxacin using drug minimum inhibitory concentrations and mutant prevention concentrations

Streptococcus pneumoniae is a prevalent cause of community-acquired upper and lower respiratory tract infections and spans all age groups. Drug-resistant pneumococcal strains have increased in prevalence, and numerous reports have documented the selection of drug-resistant strains during therapy—that is, the organism isolated from the patient was initially susceptible to the treatment antibiotic but resistance or reduced susceptibility developed during therapy [1,2].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research