The Effects of M1/M2 Macrophages on the mRNA Expression Profile of Diabetic Glomerular Endothelial Cells

Conclusion: Coculturing M1/M2 macrophages and GECs treated with AGEs can affect the mRNA expression in GECs. M2 macrophages can inhibit the Braf, Fgfr2, Map3k1, Mras, and p-ERK expression in the MAPK signaling pathway, which may be related to M2 macrophages protecting GECs from damage by AGEs.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research