Effect of maternal praziquantel treatment for < i > Schistosoma japonicum < /i > infection on the offspring susceptibility and immunologic response to infection at age six, a cohort study

We report that maternal PZQ treatment forS.japonicum shifted the PBMC immune response to a more inflammatory signature but had no impact on their offspring ’s likelihood of infection or serum cytokines at age six, further supporting the safe use of PZQ in pregnant women. Trial Registration: ClinicalTrials.gov NCT00486863.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research