Tumor location and reduction in functional MRI estimates of language laterality

CONCLUSIONS: Patients with tumors close to Broca's area showed more bilateral fMRI language maps independent of known confounders. The authors caution against the assumption that this reduced language laterality suggests no or little risk to language function following tumor resection in the left inferior frontal gyrus. Their results address how to interpret fMRI data for neurosurgical purposes, along with theoretical questions of contralesional functional compensation and disinhibition.PMID:33799298 | DOI:10.3171/2020.9.JNS202036
Source: Journal of Neurosurgery - Category: Neurosurgery Authors: Source Type: research