Molecular Characterization of Tigecycline Non-Susceptibility among Extensively Drug-Resistant < b > < i > Acinetobacter baumannii < /i > < /b > Isolates of Clinical Origin

Conclusion: It can be concluded from our results that reduced susceptibility to TGC in the studied isolates was mainly mediated by genetic alterations in the AdeRS system, which resulted in overexpression of AdeABC efflux pump. Emergence of TGC non-susceptibility among isolates that had not been previously exposed to TGC is an issue of great concern.Chemotherapy
Source: Chemotherapy - Category: Cancer & Oncology Source Type: research