Evidence for Pharmacogenomic Effects on Risperidone Outcomes in Pediatrics

Conclusion: Children and adolescents who are CYP2D6 PMs/IMs may have an increased risk for risperidone AEs. Of the genes and variants studied, only CYP2D6 has consistent association and sufficient data for clinical use, whereas HTR2A-rs6311 has limited data and requires further study.
Source: Journal of Developmental and Behavioral Pediatrics - Category: Child Development Tags: Original Article Source Type: research